Manchester City will be looking to avoid being on the receiving end of a Premier League double from Manchester United in a derby at Old Trafford that will have a significant bearing on the race for Champions League football.
While the fate of United’s season rests on their progress in the Europa League, City can only qualify for the Champions League through the Premier League and can ill-afford any slip-ups in a crowded race for the top five.
Pep Guardiola’s men are the favourites, but they will be taking little for granted after being stunned by a late turnaround from United at the Etihad Stadium earlier this season.
Check out the confirmed team news for the 4:30pm kick-off.
Manchester United team news
Harry Maguire, deployed as a makeshift striker late in the defeat to Nottingham Forest last time out, will operate in his usual role of centre-back as he takes the place of the injured Matthijs de Ligt
Much-maligned striker Rasmus Hojlund comes into the XI in place of Joshua Zirkzee, who drops to the bench.
Luke Shaw features in a United squad for the first time since December, with the England left-back named on the bench.
Manchester United XI: Onana, Yoro, Maguire, Mazraoui, Dalot, Ugarte, Casemiro, Dorgu, Bruno Fernandes, Garnacho, Hojlund.
Substitutes: Bayindir, Lindelof, Mount, Zirkzee, Eriksen, Shaw, Amass, Chido, Kukonki.
Manchester City team news
Kevin De Bruyne starts and captains City at the end of a week in which he announced he will leave the club at the end of the season.
He is into the XI as one of four changes to the side that beat Leicester City 2-0 in midweek.
The back four is unchanged, with the impressive Nico O’Reilly retaining his place at left-back.
Nico Gonzalez drops out of the City midfield, while Savinho, Jack Grealish and Jeremy Doku join him on the bench after starting on Wednesday.
Phil Foden and Bernardo Silva are back in the side and will hope to create openings for Omar Marmoush, who continues as the lone striker in Erling Haaland’s absence.
Manchester City XI: Ederson, Nunes, Dias, Gvardiol, O’Reilly, Kovacic, Gundogan, De Bruyne, Foden, Bernardo Silva, Marmoush.
Substitutes: Ortega, Gonzalez, Doku, Grealish, Savinho, Reis, Bobb, Lewis, McAtee.